PRP hair growth is a natural hair restoration solution for baldness (or alopecia). A small amount of blood is extracted with a fine needle from the individual undergoing therapy. Centrifugation is then used to separate platelet rich plasma (PRP) from the blood. When injected back into the scalp of the patient who suffers from androgenic alopecia hair loss, growth factors in PRP help in hair restoration.
PRP (PlateletRich Plasma) is a portion of plasma fraction of autologous blood having a high concentration of thrombocytes, and can be activated by Thrombin to release multiple growth factors, including platelet-derived growth factor (PDGF), vascular endothelial growth factor (VEGF), epidermal growth factor (EGF), insulin-like growth factor (IGF), and transforming growth factor beta (TGF-β). PRP is known for the capacity to stimulate cell proliferation and differentiation. The action of platelet plasma growth factors on the development of hair follicles has already been established. PRP has also been shown to increase the yield of implanted follicular units during male baldness surgery.
Small amount of blood is taken from the patient then blood is centrifuged in a machine.
Centrifugation is a process that separates components of whole blood — red blood cells (RBCs), white blood cells (WBCs) and platelets. RBCs, which make up 45% of the whole blood, rest at the bottom; with WBCs and platelets, making up <1% of the total blood, present in the buffy central layer. The top layer – called plasma – is supernatant and up to 55% of the total blood.
Once centrifuged, platelet-rich plasma (PRP) is collected by sucking out the top supernatant layer of platelet-poor plasma (PPP), the residual volume in the tube is re-suspended by gentle inversion.
PRP contains about >1,000,000/μL platelets. Total amount of PRP yielded is very small, at around 5-6 ml.
